- Andrews, Roy Chapman - naturalist (Beloit)
- Carr, Bob
- Michigan politician (Janesville)
- Comstock, John Henry - entomologist (Janesville)
- Dutton, Joseph (Brother) - ministered to
lepers on Molokai (Janesville)
- Ford, Frances
- writer of The Little Engine
That Could (Janesville)
- Hendricks, Ken
- Forbes 400 businessman; founder of ABC Supply
- Jacobs-Bond, Carrie - songwriter (Janesville)
- Jones, Darius
- football player (Beloit)
- Kenny, Jerry
- former New York Yankee (Beloit)
- Kvapil, Travis
- NASCAR driver (Janesville)
- North, Sterling - writer (Edgerton)
- Patrick, Danica - Indy driver (Beloit)
- Wilcox, Ella Wheeler - poet (Janesville)
- Willard, Frances - educator & activist (Janesville)
- Wirz, Albert
- Titanic victim
- Wright, Amy
- actress (Beloit)
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